It is important to speak to your doctor before you start using Minoxidil. This is because over-the-counter minoxidil such as Regaine is only licensed for use on hereditary hair loss (male and female pattern baldness). If you are experiencing hair loss of another kind, then treatment with minoxidil may not be suitable. Hair loss treatment with Online Doctor Based in our London office, our doctors and independent pharmacists have years of experience caring for patients in NHS hospitals, GP surgeries or in community pharmacies. Any one of the team may provide you with advice, your prescription or aftercare via private message. The AUC of 5% minoxidil foam used once daily was found to be similar to that of 2% minoxidil solution used twice daily in female subjects. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

Because of the concentration of minoxidil in Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam, accidental ingestion has the potential of producing systemic effects related to the pharmacological action of the drug (2 g of Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam contains 100 mg minoxidil; the maximum recommended adult dose for oral minoxidil administration in the treatment of hypertension). Signs and symptoms of minoxidil overdosage would primarily be cardiovascular effects associated with sodium and water retention. Tachycardia, hypotension, dizziness and lethargy can also occur. The safety of topical minoxidil from clinical trial data is based on data from 7 placebo-controlled randomised clinical trials in adults evaluating either 2% or 5% minoxidil solution, and two placebo-controlled randomised clinical trials in adults evaluating a 5% foam formulation. Adverse drug reactions (ADRs) identified during clinical trials and post-marketing experience with minoxidil are included in the table below by System Organ Class (SOC).Regaine® for Women ONCE A DAY Scalp Foam is for women with a family history of hair loss who have general thinning of hair at the top of the scalp (vertex) as shown (see leaflet for details)

Accidental ingestion may cause serious cardiac adverse events. Therefore this product has to be kept out of the reach of children. Assessment was undertaken by patients using a 100mm visual analogue scale and assessing scalp coverage where point 0 represented much less scalp coverage, 50mm no difference and 100mm much more scalp coverage. In addition, an assessment was undertaken by 2 blinded reviewers who compared photographs taken at baseline and after 48 weeks. Differences were assessed using a 7 point categorical scale viz: There is some evidence from in vitro studies that minoxidil reversibly binds to human plasma proteins. However, since only 1 – 2% of topically applied minoxidil is absorbed, the extent of plasma protein binding occurring in vivo after topical application would be clinically insignificant. The volume of distribution of minoxidil after intravenous administration has been estimated at 70 litres. The failure to detect evidence of systemic effects during treatment with Regaine Foam reflects the poor absorption of topically applied minoxidil from normal intact skin. Systemic absorption of minoxidil from topically applied solution ranges between 1% and 2% of the total applied dose. Minoxidil topical foam or solution is for use on the scalp only. Keep this medicine away from the eyes, nose, and mouth. If you should accidentally get some in your eyes, nose, or mouth, flush the area thoroughly with cool tap water. If you are using the pump spray, be careful not to breathe in the spray .As with any medicine, Minoxidil comes with some mild side effects such as mild skin irritations. However if you experience any side effects you should stop using Regaine and tell your doctor or pharmacist. It’s also important to remember that this type of hair loss treatment will not work for everyone. Regaine Extra Strength states in its Patient Information leaflet that it should be used by men aged 18-65, and that it is most likely to be effective in people who fall into the following categories: