Turmeric Powder (500g, 1.1 lb), Curcuma 100% Natural, min. of 3% curcuminoids Laboratory Tested, Gently Dried and Ground Turmeric Root, No additives, Vegan

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However, some people may experience side effects when they take them in large doses as supplements. Turmeric

Kawamori, T., Lubet, R., Steele, V. E., Kelloff, G. J., Kaskey, R. B., Rao, C. V., and Reddy, B. S. Chemopreventive effect of curcumin, a naturally occurring anti- inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res 2-1-1999;59(3):597-601. View abstract. Hu, Y., Du, Q., and Tang, Q. [Determination of chemical constituents of the volatile oil from Curcuma longa by gas chromatography-mass spectrometry]. Se.Pu. 1998;16(6):528-529. View abstract. Srinivasan, K. and Sambaiah, K. The effect of spices on cholesterol 7 alpha-hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Int.J Vitam.Nutr.Res 1991;61(4):364-369. View abstract.Large amounts of turmeric might interfere with the effects of estrogen. Taking turmeric along with estrogen might decrease the effects of estrogens. Kurien, B. T. Inhibition of p300 and nuclear factor-kappaB by curcumin and its role in diabetic nephropathy. Nutrition 2009;25(9):973-974. View abstract.

Turmeric’s root stalks, called rhizomes, are bright yellow or orange. They’re usually dried and ground into powder. Flynn, D. L., Rafferty, M. F., and Boctor, A. M. Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. Prostaglandins Leukot.Med. 1986;22(3):357-360. View abstract. Jayasekera, R., Freitas, M. C., and Araujo, M. F. Bulk and trace element analysis of spices: the applicability of k0-standardization and energy dispersive X-ray fluorescence. J Trace Elem.Med.Biol. 2004;17(4):221-228. View abstract. Turmeric might lower blood sugar levels. Taking turmeric along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely. Panahi, Y., Sahebkar, A., Parvin, S., and Saadat, A. A randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complications. Ann.Clin Biochem. 2012;49(Pt 6):580-588. View abstract.Pure turmeric is considered safe for most people. However, turmeric powders may sometimes be adulterated with cheap fillers, such as wheat starch and questionable food colorants. They may even contain lead. Garcea, G., Berry, D. P., Jones, D. J., Singh, R., Dennison, A. R., Farmer, P. B., Sharma, R. A., Steward, W. P., and Gescher, A. J. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol.Biomarkers Prev. 2005;14(1):120-125. View abstract. Pungcharoenkul, K. and Thongnopnua, P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Phytother Res 2011;25(11):1721-1726. View abstract. Sreejayan and Rao, M. N. Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol 1994;46(12):1013-1016. View abstract. Huang, H. C., Jan, T. R., and Yeh, S. F. Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation. Eur.J Pharmacol. 10-20-1992;221(2-3):381-384. View abstract.

One study suggests that curcumin supplements may induce a gene that can cause decreased levels of certain antidepressant and antipsychotic medications ( 35). Turmeric might increase how much sulfasalazine the body absorbs. Taking turmeric while taking sulfasalazine might increase the effects and side effects of sulfasalazine.

Turmeric can also lower blood sugar and may enhance the effects of antidiabetic drugs or insulin ( 10). Shoskes, D. A. Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation 7-27-1998;66(2):147-152. View abstract. Shimouchi, A., Nose, K., Takaoka, M., Hayashi, H., and Kondo, T. Effect of dietary turmeric on breath hydrogen. Dig.Dis.Sci. 2009;54(8):1725-1729. View abstract. That said, research on possible drug interactions with curcumin is limited and doesn’t provide enough evidence to say with certainty whether taking curcumin supplements interacts with other medications you may be taking.