Herpatch Cold Sore Treatment Serum - Treat & Prevent Coldsores - Cold Sore Cream Alternative - Heals in 24 Hrs - Relieves Pain, Reduce Swelling & Blistering - Clinically Proven - inc SPF 30 Lip Balm.

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Khemis, A. et al. Evaluation of the efficacy and safety of a CS20 (R) protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial. J. Eur. Acad. Dermatol. 26, 1240–1246 (2012). Finally, zinc sulphate reduces pain and itching and has an astringent action, which firms, tones and strengthens the skin. Zinc sulfate will therefore also help to accelerate healing of cold sore lesions. Arduino, P. G. & Porter, S. R. Herpes Simplex Virus Type 1 infection: overview on relevant clinico-pathological features. J. Am. Acad. Dermatol. 37, 107–121 (2008). Raborn, G. W. et al. Effective treatment of herpes simplex labialis with penciclovir cream: combined results of two trials. J. Am. Dent. Assoc. 133, 303–309 (2002). Herpatch Herpes Serum temelji se na ciljanoj tehnologiji tekuće obloge. Nakon nanošenja pretvara se u tanak i proziran, ali jak i čvrst zaštitni sloj preko zahvaćene površine na koji način nastaje idealno mikro-okruženje. Sastojci će odmah oblikovati jak zaštitni film koji će prekriti herpes, izazvan virusom Herpes simplex. Dobrobiti upotrebe su: smanjenje vidljivosti rubova rane, smanjenje eritema, obuzdavanje boli i osjećaj ugode u bolesnika.

Aktivni kisik ubrzava obnovu stanica, povećava hidrataciju kože i stoga smanjuje vrijeme zacjeljivanja oboljele površine izazvane herpesom; The lesion stage (precursor lesion, macule, papule, vesicle, ulcer, soft scab, hard scab) was classified by the clinician on each examination day. At the end of the observation period (day 10), the clinician, using the Clinician’s Global Assessment of Therapy (CGAT) evaluated the reaction rate (assessment of the speed of effectiveness of the product) and the reaction quality (assessment of the effectiveness of the product). This assessment was taken over from a clinical trial by Karlsmark et al. 22.Junker, J. P. E., Kamel, R. A., Caterson, E. J. & Eriksson, E. Clinical Impact Upon Wound Healing and Inflammation in Moist, Wet, and Dry Environments. Adv. Wound Care 2, 348–356 (2013). Tang, W. & Bhushan, B. Adhesion, friction and wear characterization of skin and skin cream using atomic force microscope. Colloids Surf. B 76, 1–15 (2010). Faul, F., Erdfelder, E., Buchner, A. & Lang, A. G. Statistiacal power analysis using G*Power 3.1: Test for correlation and regression analyses. Behav. Res. Methods 41, 1149–1160 (2009). Sulfatizirani polisaharid, pridobljen iz rdečih mikroalg, tvori aktivno zaščitno pregrado in pomaga varovati pred sončnimi žarki.

I have suffered from cold sores ever since I can remember for 37 years and have tried and tested various projects self remedies homoeopathic remedies, creams patches etc. I have to commend you on your herpatch serum as it is the only thing I've ever found that does not eliminate my cold sores but absolutely certainly reduces the amount of time and the damage that they cause to my mouth and lips- thank you very much please don't stop making it or I'm done for! Van Vloten, W. A., Swart, R. N. & Pot, F. Topical acyclovir therapy in patients with recurrent orofacial herpes simplex infections. J. Antimicrob. Chemother. 12, 89–93 (1983). The treatment of recurrent HSL turns out to be very difficult and variable. Because of the slight effects of diverse therapies, the infection represents a constant and global public health problem 9. Episodic therapy can be used for relief of accompanying symptoms 10. Therefore, several topical applications, such as phytotherapeuticals, natural remedies, photodynamic therapy, heat and laser application, as well as antiviral substances, can be provided 11– 16. Zahvaljujući inovativnom i učinkovitom načinu nanošenja, serum Herpatch Herpes Serum stručnjak je za liječenje herpesa na usnama.

Serum za herpes na usnama

Arenberger, P., Arenbergerova, M., Hladikova, M., Holcova, S. & Ottillinger, B. Comparative Study with a Lip Balm Containing 0.5% Propolis Special Extract GH 2002 versus 5% Aciclovir Cream in Patients with Herpes Labialis in the Papular/Erythematous Stage: A Single-blind, Randomized, Two-arm Study. Curr. Ther. Res. Clin. E. 88, 1–7 (2018).

Herpes simplex labialis (HSL) is a worldwide infection of the oral and perioral regions caused by an infection with Herpes Simplex Virus type 1 (HSV-1) or, rarely, Herpes Simplex Virus type 2 (HSV-2). Despite the high prevalence of HSL, the disease has not yet been well characterized. The seroprevalence of HSV-1 in Germany was 78.4% from 2008 until 2011 1, 2. While many infections remain subclinical, other patients suffer from painful recurrent infections. Raborn, G. W. & Grace, M. G. Recurrent herpes simplex labialis: selected therapeutic options. J. Can. Dent. Assoc. 69, 498–503 (2003). Honarmand, M., Farhadmollashahi, L. & Vosoughirahbar, E. Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis. J. Clin. Exp. Dent. 9, 729–732 (2017).Carson, C. F., Ashton, L., Dry, L., Smith, D. W. & Riley, T. V. Melaleuca alternifolia (tea tree) oil gel (6%) for the treatment of recurrent herpes labialis. J. Antimicrob. Chemother. 48, 450–451 (2001). Active oxygen will accelerate cell renewal, will increase the moisture in the skin and therefore decrease the healing time of cold sore lesions; U.S. Food and Drug Administration. ZOVIRAX (acyclovir) cream 5% for topical use - Reference ID: 3481551 (2014).

An alternative is provided in the Compeed Invisible Cold Sore Patches that include no antiviral ingredient (Compeed; Johnson & Johnson Santé Beauté France SAS, Sézanne, France). The cytotoxicity was tested on fibroblasts. Further studies examined the irritation of the patches on rabbits and the sensitivity on guinea pigs. The outer layer of the patch consists of a semiocclusive polyurethane film, which allows excessive wound exudate to evaporate while keeping the lesion moist, ensuring an optimum moisture level. The patch seals the wound and arranges ideal conditions for wound healing. The patch functions as a shield, protecting surrounding areas from infection. As soon as the first symptoms occur, the patch is placed on the lesion, replaced if required, and worn for 24hours until complete healing occurs 19. The Kolmogorov-Smirnov, Kruskal-Wallis, and Mann-Whitney U tests were used to determine the existence of statistically significant differences among the three tested products regarding the secondary endpoint. After Bonferroni correction, the probability of error p and the level of significance were defined as p = 0.025. Arduino, P. G. & Porter, S. R. Oral and perioral herpes simplex virus type 1 (HSV-1) infection: review of its management. Oral Dis. 12, 254–270 (2006). An alternative is provided in the Compeed Invisible Cold Sore Patches that include no antiviral ingredient (Compeed; Johnson & Johnson Santé Beauté France SAS, Sézanne, France). The cytotoxicity was tested on fibroblasts. Further studies examined the irritation of the patches on rabbits and the sensitivity on guinea pigs. The outer layer of the patch consists of a semiocclusive polyurethane film, which allows excessive wound exudate to evaporate while keeping the lesion moist, ensuring an optimum moisture level. The patch seals the wound and arranges ideal conditions for wound healing. The patch functions as a shield, protecting surrounding areas from infection. As soon as the first symptoms occur, the patch is placed on the lesion, replaced if required, and worn for 24 hours until complete healing occurs 19.

Dreno, B., Malkin, J. E., Saiag, P. & Batuji-Garin, S. Patient´s profile, burden of disease and quality of life in recurrent herpes labialis: a survey conducted in USA and France. J. Eur. Acad. Dermatol. 26, 1458–1460 (2012). Besides the film-forming ingredients a number of other substances have been incorporated in Herpatch Cold Sore Serum : Herpatch Herpes Serum možete izravno i jednostavno nanijeti na herpes zahvaljujući aplikatoru u obliku tube. Nakon nekoliko minuta bijela krema stvara zaštitni i prozirni film preko mjehurića od herpesa te pomoću sastojaka pomaže u ubrzavanju procesa zacjeljivanja. Herpatch Herpes Serum djeluje na simptome u svim fazama izbijanja herpesa. Zupin, L. et al. Antiviral properties of blue laser in an in vitro model of HSV-1 infection. Microbiol. Immunol. (2018). The statistical analysis of the reaction rate and the reaction quality showed statistically significant differences between Herpatch and Compeed as well as between Herpatch and Zovirax, both in favour of Herpatch. Karlsmark et al. evaluated the same parameters without assessing statistically significant differences between Compeed and Zovirax 22. Hydrocolloid wound dressings such as the Compeed patches promote re-epithelialization and reduce inflammatory responses 41, 42. However, in this clinical trial, the patch had to be removed several times due to the patch margins peeling off. This was caused particularly by liquids such as saliva, food or drinks or by facial expressions. The peeled-off margins led to discomfort and caused the patient to renew the patch. With every replacement, already formed crusts were torn off with the patch, causing pain while promoting primary wound healing. Accompanying symptoms such as pain, tingling, swelling, or burning were also assessed in comparable trials 43, 44. The duration and intensity of symptoms were rated and showed comparable distributions independent of the applied product. This evaluation is important to prove the effective impact of treatment on healing.