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BRITA MAXTRA+ replacement water filter cartridges, compatible with all BRITA jugs -reduce chlorine, limescale and impurities for great taste - 3 pack

£3.33£6.66Clearance
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In rats, the oral LD 50 is 680 ug/kg and the subcutaneous LD 50 is 1630 ug/kg. In mice, the oral LD 50 is 4700 ug/kg, the intraperitoneal LD 50 is 48 mg/kg, and the subcutaneous LD 50 is 34 mg/kg. Ans : Yes, this syrup is beneficial for cough conditions. It also treats other issues such as sinus pressure, watery eyes, hay fever and allergies. Chlorphenamine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from: Maxtra is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa. Maxtra binds to α 1- and α 2-adrenoceptors, which are Gq-protein-coupled receptors that promote vascular smooth muscle contraction by increasing intracellular calcium levels in response to ligand activation.

The syrup can cause excessive drowsiness and calmness if you consume alcohol while under medication. Therefore, you must avoid it as much as possible while taking this syrup

Pregnancy & Breastfeeding use

Ans : There are some side effects of this syrup. It can cause some other allergies or unwanted effects. Some of them are: Nausea, Irregularity of heartbeats, Vomiting, Increased heart rate, Headache, Palpitations, Constipation, Stomach ache, Blurred vision, Swelling of face, Shortness of breath, Loss of consciousness.

Maxtra Syrup 60 ml contains Chlorpheniramine and Phenylephrine. Chlorpheniramine is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Phenylephrine is a decongestant that narrows the small blood vessels, relieving the nose's congestion or stuffiness. Together, Maxtra Syrup 60 ml effectively reduces allergic symptoms. To see the full effect of medicine, it can take more than 6 hours or even more than 2 days in some cases. Therefore, it is advisable that you change your dosage according to your interaction with the syrup. Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.Maxtra Syrup 60 ml can be taken with or without food in a dose and duration as advised by the doctor. The most common side effects of Maxtra Syrup 60 ml are drowsiness, dizziness, headache, dry mouth/nose/throat, upset stomach, constipation, or trouble sleeping.Most of these side effects of Maxtra Syrup 60 ml do not require medical attention and gradually resolve over time. however, if the side effects are persistent, reach out to your doctor. Two-litres+: for families, those who drink lots or if you don’t want to keep refilling the jug throughout the day This medicine provide temporary relief of nasal congestion and eustachian tube congestion along with the associated symptoms. Maxtra Syrupmay cause drowsiness. Avoid driving or operating machinery while taking this medication. The answer to this question very much depends on the brand and model of your water filter jug. It also depends on how often you’re using it. Some water filters come with indicators to let you know it’s time to change it, which is useful. But, all new water filters will let you know how long the filter is supposed to last, this is typically displayed in months and filters can last anywhere from two to six months. The duration of the effect can differ from person to person and the dosage as well. A doctor will guide you better in this regard with the amount and frequency of dosage that best suits you.

There is no sufficient information about the possible side effects of how this syrup can affect breastfeeding women in general. Therefore, you must consult your doctor before consumption. Phenylephrine- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from: Ans : It is a combination of two different drugs (Chlorpheniramine 2 mg/ml, Phenylephrine 5 mg/ml) which used to treat conditions such as Nasal De-congestion, Common cold and Flu-like symptoms.

How Maxtra works

Maxtra Syrup 60 ml belongs to the combination medication called 'anti-allergics' primarily used to treat symptoms caused by the common cold, flu, allergies and other breathing problems like sinusitis and bronchitis. An allergy is an immune system response to foreign elements typically not harmful to your body. These foreign elements are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever. At the same time, others might be allergic to pollen or pet dander.

Drug-Drug Interactions:Maxtra Syrup 60 ml have interactions with other anti-allergic medications (cetirizine, fluticasone, diphenhydramine), blood thinners (aspirin), cough suppressant drugs (dextromethorphan), anti-hypertensive medications(atorvastatin), anti-asthma medications (albuterol), medicines used for stomach problems (pantoprazole), anti-depressants (isocarboxazid, rasagiline, linezolid, tranylcypromine).Maxtra is an adrenergic α1- and α2-agonist and a direct-acting sympathomimetic drug. By stimulating adrenergic receptors, oxymetazoline causes vasoconstriction of dilated arterioles and reduces blood flow. In a radioligand competition study, oxymetazoline displayed higher affinity at α1A-adrenoceptors compared to α2B-adrenoceptors, but with higher potency at α2B-adrenoceptors. When sprayed intranasally, oxymetazoline relieved relief nasal congestion and improved nasal airflow in patients with acute coryzal rhinitis for up to 12 hours following a single dose. Apart from this, high blood pressure, seizures, overactive thyroid, stomach problems or urination problems also. Up to 10% of patients could experience tachycardia, palpitations, and dry mouth; use vasoconstrictor with caution; prolonged use will cause significant xerostomia. Imidazole derivatives such as oxymetazoline are readily absorbed across mucosal membranes, especially in children. In adult subjects with erythema associated with rosacea, the mean ± standard deviation (SD) C max was 60.5 ± 53.9 pg/mL and the AUC from time 0 to 24 hours (AUC 0-24hr) was 895 ±798 pg x hr/mL following topical administration of first-dose oxymetazoline. Following once-daily topical applications for 28 days, the mean ± SD C max was 66.4 ± 67.1 pg/mL and the AUC 0-24hr was 1050 ± 992 pg x hr/mL. Following twice-daily applications for 28 days, the mean ± SD C max was 68.8 ± 61.1 pg/mL and the AUC 0-24hr was 1530 ± 922 pg x hr/mL. Ans : It is an antihistamine which restricts the action of histamine and work as a reliever from the symptoms such as Sinus pressure, Sinus congestion, Running nose, Throat itching, Hay fever, Allergies, sneezing because of respiratory infections, Watering eyes, Cough.

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